![]() ![]() Traditional Chinese medicine (TCM) has been widely used in ethnic communities for the treatment of a variety of diseases and it is recognized as an attractive alternative to conventional medicine ( Tang and Eisenbrand, 1992 Chan, 1995 Cheng, 2000 Yuan and Lin, 2000 Bhuiyan et al., 2003 Wang et al., 2003 Lazar, 2004). traditionally defined herbal properties.traditional Chinese medicine information database.The database and its mining applications described here represent early efforts toward exploring TCM for new theories in drug discovery.īritish Journal of Pharmacology (2006) 149, 1092–1103. TCM offers an extensive source of examples of this concept in which several active ingredients in one prescription are aimed at numerous targets and work together to provide therapeutic benefit. The development of systems biology has led to a new design principle for therapeutic intervention strategy, the concept of ‘magic shrapnel’ (rather than the ‘magic bullet’), involving many drugs against multiple targets, administered in a single treatment. The value of the data in TCM-ID was illustrated by using some of the data for an in-silico study of molecular mechanism of the therapeutic effects of herbal ingredients and for developing a computer program to validate TCM multi-herb preparations. TCM-ID currently contains information for 1,588 prescriptions, 1,313 herbs, 5,669 herbal ingredients, and the 3D structure of 3,725 herbal ingredients. The Traditional Chinese Medicine Information Database TCM-ID, at, was introduced for providing comprehensive information about all aspects of TCM including prescriptions, constituent herbs, herbal ingredients, molecular structure and functional properties of active ingredients, therapeutic and side effects, clinical indication and application and related matters. We manually collected information on TCM in books and other printed sources in Medline. Quantitative information about TCM prescriptions, constituent herbs and herbal ingredients is necessary for studying and exploring TCM. ![]() Traditional Chinese Medicine (TCM) is widely practised and is viewed as an attractive alternative to conventional medicine. ![]()
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